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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYST
All Species:
7.58
Human Site:
S2113
Identified Species:
23.81
UniProt:
Q99698
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99698
NP_000072.2
3801
429139
S2113
L
P
A
F
P
T
S
S
L
L
T
Q
S
Q
K
Chimpanzee
Pan troglodytes
XP_514288
3802
429200
S2114
L
P
A
F
P
T
S
S
L
L
M
Q
S
Q
K
Rhesus Macaque
Macaca mulatta
XP_001110270
2122
239689
Q564
Q
C
L
R
L
L
Q
Q
A
S
L
S
S
T
C
Dog
Lupus familis
XP_536337
3800
429431
S2112
L
P
A
F
P
T
A
S
P
R
V
Q
P
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
P97412
3788
425269
L2107
L
P
A
F
P
T
Y
L
P
L
I
R
A
Q
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419558
2576
290128
H1018
G
R
T
V
F
E
G
H
S
E
T
I
K
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919653
3830
427741
L2146
S
P
H
S
S
P
A
L
T
P
R
L
T
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392306
3271
364901
V1713
S
Q
L
N
R
I
G
V
V
D
T
V
L
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
53.7
90.8
N.A.
84.9
N.A.
N.A.
N.A.
51.5
N.A.
61.3
N.A.
N.A.
24.2
N.A.
N.A.
Protein Similarity:
100
99.4
55.1
95.5
N.A.
91.7
N.A.
N.A.
N.A.
58.7
N.A.
75.9
N.A.
N.A.
41.8
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
66.6
N.A.
60
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
73.3
N.A.
73.3
N.A.
N.A.
N.A.
13.3
N.A.
20
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
25
0
13
0
0
0
13
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
13
% C
% Asp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
13
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
50
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
25
0
0
0
0
0
0
0
13
% G
% His:
0
0
13
0
0
0
0
13
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
13
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
50
% K
% Leu:
50
0
25
0
13
13
0
25
25
38
13
13
13
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
63
0
0
50
13
0
0
25
13
0
0
13
0
0
% P
% Gln:
13
13
0
0
0
0
13
13
0
0
0
38
0
50
0
% Q
% Arg:
0
13
0
13
13
0
0
0
0
13
13
13
0
13
0
% R
% Ser:
25
0
0
13
13
0
25
38
13
13
0
13
38
0
0
% S
% Thr:
0
0
13
0
0
50
0
0
13
0
38
0
13
25
0
% T
% Val:
0
0
0
13
0
0
0
13
13
0
13
13
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _